Since 2020, aggregated from related topics
Short-chain fatty acids (SCFAs) are a group of fatty acids with fewer than six carbon atoms, primarily acetate, propionate, and butyrate. SCFAs are produced in the gut by microbial fermentation of dietary fiber and play a crucial role in maintaining gut health and overall wellbeing. They serve as a major energy source for colonocytes, regulate immune responses, modulate inflammation, and influence hormone production. Research in this area aims to better understand the mechanisms by which SCFAs impact human health and explore potential therapeutic applications in various conditions, such as inflammatory bowel disease, obesity, and metabolic disorders.